Research

Our research philosophy

Pelago is dedicated to delivering safe and effective care for our members. In order to do so we turn to science, conducting research and peer-reviewed studies. Substance use disorders can be treated in a variety of ways, including social support, therapy, medication or a combination of treatments. But what is the most effective? Through rigorous research, we validate and refine our treatment approaches, leveraging outcomes of scientific inquiry to guide custom solutions for each individual who participates in our programs.

We’ve found some interesting results so far and we encourage you to take a look at the data yourself.

52%

biochemically-verified quit rate at 28 days

44%

biochemically verified quit rate at 26 weeks post-quit date

71%

more likely to remain abstinent from tobacco at 12 months

06/19/2025Glasner et al. / Liebert

Economic Impact of an Employer-Sponsored Integrated Digital Intervention Targeting Substance Use Disorders

Change in Substance Use Treatment Costs

Baseline
Year 1

$6,758

Average medical cost savings per participants over 12 months

4.5:1

Return on investment in 12 months (including Pelago program fee)

33%

Lower medical spend driven by fewer inpatient, outpatient, and ER claims

05/29/2024Monico et al. / Digital Health

Feasibility and acceptability of a novel digital therapeutic combining behavioral and pharmacological treatment for opioid use disorder

Number of Abstinent Days (past 30)

0 Days
1-10 Days
11-20 Days
21-29 Days
30 Days

67%

abstinent over 90 days

95%

average medication adherence

overall decrease in depression & anxiety

overall increase in well-being

09/09/2023Glasner et al. / Springer

Implementing Suicide Risk Screening in a Virtual Addiction Clinic

Virtual Suicide Research Screening

252

Screened patients

7.5%

Screen-positive rate

100%

of clinicians were comfortable asking patients about suicidal thoughts and behaviors

04/19/2023Webb et al. / Liebert

Feasibility and Preliminary Outcomes of a Mobile Intervention Combining Cognitive Behavioral Therapy, Virtual Coaching, and Nicotine Replacement Therapy for Nicotine Vaping Cessation

87%

of participants quit vaping

time vaping decreased from 75.8 minutes to 26.5 minutes

days vaping decreased from 24.7 to 3.9

11/04/2022Glasner et al. / Liebert

Feasibility, Acceptability, and Preliminary Outcomes of an Integrated Telemedicine Intervention Combining Naltrexone and Cognitive Behavioral Therapy for Alcohol Use Disorder

Changes in mean percentage of days abstinent

Days Abstinent

68%

of participants reduced their alcohol use

drinks per day decreased from 6.7 to 2.7

96%

participation and satisfaction

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